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Director’s Situation Update

Monday

11 May 2009 1100 EDT 

Day 23

Day of Vaccine Planning

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Novel Influenza A (H1N1) Key Events

11 May 2009 

Novel Influenza A (H1N1) Declarations

WHO: Pandemic Phase 5 (29 Apr 1600 EDT)

Declarations of Emergency (no changes)

USG: Public Health Emergency declared  (26 Apr 2009)

SLTT Declarations: 10

– CA, TX, WI, FL, NE, VA, MD, IA, OH, American Samoa

National Declarations: 4

– Ecuador, Costa Rica, Colombia, Mexico

US Cases:  

Confirmed: 2,618 cases (

ç

86)

2,614 cases, 43 States; 4 cases DC 

Probable: 704 cases

698 cases, 40 States; 6 cases DC 

Confirmed/Probable: 3,322 cases (

è

75)

3,312  cases, 46 States; 10 cases DC 

Third fatality in US identified in WA 

Total Deaths 3: (2-TX, 1-WA )

International Cases: 4,694 in 30 Countries

New countries with confirmed cases: Norway, China

Deployments: 116 deployed, 34 pending

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Novel Influenza A (H1N1) 

11 May 2009 

Strategic Objectives / Principles

1. Reduce illness and death

2. Minimize societal impact

3. Put greatest effort in activities with greatest 

impact

Zones of Effort

1. Understanding the problem

2. Public Health Interventions

3. Communications

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Epidemiology/Surveillance Team

Novel Influenza A (H1N1)  Cases as of 11 May 2009 1100 EDT

# State 

Cases

States

# DC 

Cases

TTL 

States+DC

# State 

Cases

States

# DC 

Cases

TTL 

States+DC

# State 

Cases

States

11-May

2,614

 43

4

2,618

     

93

21

1

94

         

3

2

Change 

(5/10 to 5/11)

86

0

0

86

(-4)

0

0

(-4)

0

0

# State 

Cases

States

# DC 

Cases

TTL 

States+DC

# State 

Cases

States

# DC 

Cases

TTL 

States+DC

# State 

Cases

States

11-May

3,312

 46

10

3,322

     

109

24

1

110

3

2

Change 

(5/10 to 5/11)

(-75)

0

0

(-75)

(-10)

0

0

(-10)

0

0

Confirmed (CDC Lab)

Total Confirmed and Probable

Cases

Hosp Deaths

Cases

Hosp Deaths

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0

20

40

60

80

100

120

140

160

180

200

220

28-

M

ar

30

-Ma

r

1-Ap

r

3-A

pr

5-

A

pr

7-

A

pr

9-A

pr

11

-A

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13

-A

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15

-Ap

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17

-A

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19

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23

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-A

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27

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-Ap

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1-

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D

Date of Illness onset

lness Onset

N

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. o

f C

a

s

e

s

Confirmed

Probable

Underreporting over weekend: 
No. states reporting: 
May 9, n=24 
May 10, n=21 

Epidemiology/Surveillance Team 

Cases by Date of Onset as of 11 May 2009 1100 EDT

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Epidemiology/Surveillance Team 

Age Group by Case Status as of 11 May 2009 1100 EDT

0

100

200

300

400

500

600

700

0-4 years

5-17 years 18-49 years 50-64 years >=65 years

Age

Nu

m

b

e

r o

f Ca

s

e

s

Confirmed

Confirmed and Probable

*Age available for 962/2618 confirmed and 244/704 probable cases. 

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Epidemiology/Surveillance Team 

Confirmed Cases Descriptive Statistics as of 11 May 2009 1100 EDT

– Median age: 15 years, range 1 month- 86 years

– 62% (633/1026): age <18 years 

– 16 cases: age <12 months

– Gender: 49% female

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NOTE: Week ending dates vary by influenza season

*Preliminary ILI data for week 17, as of May 10, 2009 (n=1,081 weekly ILI reports received from 50 states)

† There was no week 53 during the 2006-07 and 2007-08 seasons, therefore the week 53 data point for those seasons is an average of weeks 52 and 1.

% ILI Visits Reported by US Outpatient Influenza-like Illness Surveillance Network (ILINet), 

National Summary 2008-09 and Previous Two Seasons

(No updates since last report)

0

1

2

3

4

5

6

7

10

/4

10

/1

8

11

/1

11

/1

5

11

/2

9

12

/1

3

12

/2

7

1/

10

1/

24

2/

7

2/

21

3/

7

3/

21

4/

4

4/

18

5/

2

5/

16

Week Ending Dates

%

 o

f V

is

its

 fo

IL

2006-07†

2007-08†

2008-09

National Baseline

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Epidemiology/Surveillance 

Assessment & Planning 11 May 2009

• Assessment:

– Current case counts represent low case reporting 

by states May 9-10 

– Expect significant increase in numbers reported 

May 11 

• Plan:

– Continuing to review general epi trends as well as 

info from HCP and pregnancy activities

– Anticipating additional data from field studies 

over next several days, including household 
attack rates, estimates of duration of symptoms 
from shedding study

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International

Novel Influenza A (H1N1) - 11 May 2009

WHO global case count: 4,694 confirmed cases in 30 countries*

– No major increase in cases since yesterday’s report

– New countries with confirmed cases: 

Norway, China

**

– China’s first confirmed case:

• 30 y.o. male studying at unspecified US university

• Departure flight from US was out of St. Louis

– Countries with highest confirmed case count after the US and 

Mexico:

• Canada: 284 (

ç

4) Spain: 95 (=) UK: 47 (

ç

4)

Two documents being finalized

– Research Agenda for Tropics and Southern Hemisphere

– CDC Strategy for H1N1 Pandemic Mitigation in the Imminent 

Southern Influenza Season

*Note: WHO case counts are current as of 05/11/09, 6:00 am EDT

**First case in mainland China. 1 case previously confirmed in 
Hong Kong.

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Division of Global Migration and Quarantine

Novel Influenza A (H1N1) - 11 May 2009

Ports of Entry (POEs)

– 157 response events, 15 confirmed after referral at POE 

(10 May) 

– Hawaii DOH conducting enhanced sentinel 

surveillance: 

• Swabs for arriving domestic and international travelers 

with ILI symptoms

– Positive travelers encouraged to self-isolate

Community Mitigation (CM)

– Epi-Aids: NPI  - NY, Chicago, Delaware

– Ft Worth School closure evaluation under review

– Community Mitigation Team arrived Mexico City, 9 May

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Vaccine

Novel Influenza A (H1N1) - 11 May 2009

• Activities

– Developing recommendations around use of 

remaining 2008-09 Northern Hemisphere seasonal 
vaccine (week of 5/11/09)

• Plans Unit mission analysis 

• Strategy meeting on unintended consequences

• ACIP influenza work group call

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Animal/Human

Novel Influenza A (H1N1) - 11 May 2009

• High Pathogenic Avian Influenza  (HPAI)

– H5N1 OIE confirmed outbreaks in past 3 

weeks

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*WHO, May 6, 2009: 423 cases total, 258 fatal (61.19%)

Human Cases of Avian Influenza 

Human Cases of Avian Influenza 

H5N1 2003

H5N1 2003

-

-

2009*

2009*

4

32

43

79

59

33

8

0

14

55

36

29

11

20

0

20

40

60

80

100

120

2003

2004

2005

2006

2007

2008

2009

Fatal

Non-Fatal

88

115

98

46

4

44

28

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Communications Summary

Novel Influenza A (H1N1) - 11 May 2009

Domestic Communication 

Channel Traffic

Web Page Views: 729, 366 (-49%)

Public Inquires: 290 (-55%)

Print/Internet News Stories: 241 (-3%) 

National Television Stories: 26 (+63%)

Local Television Stories: 320 (-20%)

Themes

Print/Internet—Focus on International 

Themes

New flu kills US man, spreads to 

Australia, Japan 

Emerging themes (all news channels)

Criticism of warning system – WHO 

needs  mechanism to dial down the 
anxiety levels while educating about the 
extent of  transmission.

Spanish Language Media Monitoring 

(global outlets; machine translation) 

Coverage, generally non-sensational, 

factual, and non-critical

Case count continues to mount 
rapidly

Secondary  transmission instances 
noted in Europe 

Illness course  mild-moderate and 
self-limiting 

Fatal cases (Costa Rica, Canada) in 
presence of underlying (chronic) 
disease or disorder

Economic losses in Mexico, 
substantial though effort underway 
to “normalize” activities 

Public Inquiries: CDC-INFO emails/calls 

Symptoms? 23%

Incubation Period?  

12% 

Travel recommendations?

10%